A Clinical Study of HbA1c as the Marker of Circulating Lipids in Type 2 Diabetes Patients.

Dr. Jayamohan Kokkat; Dr. Henley Punnen Andrews; Dr. P S Prakash; Dr. Anoop Many; Dr. Bibin P; Dr. Sandheep George Villoth

Volume : VI, Issue : VII, July - 2017

A Clinical Study of HbA1c as the Marker of Circulating Lipids in Type 2 Diabetes Patients.

Dr. Jayamohan Kokkat, Dr. Henley Punnen Andrews, Dr. P S Prakash, Dr. Anoop Many, Dr. Bibin P, Dr. Sandheep George Villoth

Abstract :

Aims: The objective of this study was to determine the correlation of HbA1c with circulating lipids in patients with Type 2-diabetes and to find out whether HbA1c can be used as a predictor of circulating Lipids in T2DM. Materials and Methods: The research used a sample of 100 patients who had fulfilled the inclusion criteria and got admitted in a tertiary medical college hospital in south India. HbA1c and FLP tests were done and their relation was analysed.

Statistical analysis used: Data analysis was done using a method that is standardized and certified by the NGSP, to determine the correlation between HbA1c and each variable in the FLP. The respective scatter plot was designed with a regression analysis. A follow up study was done after a period of six months to analyze how each variable in FLP was changing with variation in HbA1c. This was done by Spearman�s Rho and Pearson�s correlation test.

Results: The results indicated a positive correlation between HbA1c and S. Cholesterol, LDL and TG. There was a negative correlation between HbA1c & HDL. That is, higher the HbA1c value, lower was the value of HDL. In the follow up study, it was found that increase or decrease of HbA1c was associated with a corresponding increase or decrease in S. Cholesterol, LDL and TG. A Negative correlation of HbA1c with HDL was shown only in the female population in the follow up study. Conclusions: The study concluded that HbA1c could be used as a predictor of Dyslipidemia among the type 2-diabetes patients.