A correlation between Serum Adiponectin level and Type 2 Diabetes: A Meta- Analysis of 5403 subjects

Akanksha Dubey; Dr P. J. Hisalkar

Volume : VII, Issue : I, January - 2018

A correlation between Serum Adiponectin level and Type 2 Diabetes: A Meta- Analysis of 5403 subjects

Akanksha Dubey, Dr P. J. Hisalkar

Abstract :

The increasing prevalence of Type 2 Diabetes has become a major public health challenge throughout the world, with 366 million prevalent diabetic cases in 2011 and a projected 552 million cases expected by the year 2030^[1]. Both lifestyle factors, including diet and physical activity, and genetic factors contribute to the accelerating diabetes epidemic^[2]. The designation of the adipose tissue as a pivotal active endocrine organ has indeed drawn much scientific interest in the last few years. The adipose tissue is now viewed as the largest endocrine organ in the body ^[3] It secretes numerous bioactive proteins, collectively known adipocytes, into the circulation. ^[4] The most abundant of these adipo-cytokines is the adiponectin which is secreted by white adipose tissue and accounts for 0.01% of total plasma proteins. ^{[5, 6]}