Volume : VII, Issue : XII, December - 2018

A Paper on Ulcerative Colitis

Dr. Archana Maan Kaushik, Dr. Vikash Kaushik

Abstract :

 

It is a chronic inflammatory bowel disease consisting of fine

ulceration in the inner mucosal lining of the large

intestine.Inflammation starts at the lower end of the colon ,just above

the anus and extends upward in a continuous manner to variable

distances.The terminal ileum is typically not involved but some

patient with extensive disease may show endoscopic signs of

“backwash ileitis”.

When only a small portion of the lower intestineis involved then it is

named as Ulcerative Proctitis,it is a milder form of the disease.

UC is unrelated to ulcers found elsewhere in the gastrointestinal

tract,such as stomach and duodenal ulcers,but it has many similarty to

Crohn’s disease.

In 95% of cases the disease starts in rectum and spreads proximally.

It is a diffuse inflammatory disease,firstly affecting the mucosa and

superficially submucosa.

Deeper layer of intestine wall is only affected in serious condition.

There are multiple minute ulcers and microscopic evidences proves

that the ulceration is almost always more severe and extensive than

the gross appearance indicates.

Cancer risk in colitis :

At 10 years ,the risk of cancer in all patients with UC IS 2%.This

increase to 8% at 20 years and 18%at 30 years.It is more likely to

occur if the whole colon is involved and if the disease starts in early

 

life.The colon is involved rather than the rectum,and the maximal

incidence is during the fourth decade.

Keywords :

Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

A Paper on Ulcerative Colitis , Dr.Archana Maan Kaushik, Dr. Vikash Kaushik , GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-7| Issue-12 | December-2018

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