A Study of Hepatitis A and Hepatitis E virus in clinically suspected cases of Acute Viral Hepatitis at A Tertiary Care Hospital.

Dr. Jayshri Pethani; Dr. Hitarthi Mehta; Dr. Komal Dholaria; Dr. Atit Shah; Dr. Bimal Chauhan; Dr. Lata Patel

Volume : VII, Issue : XII, December - 2018

A Study of Hepatitis A and Hepatitis E virus in clinically suspected cases of Acute Viral Hepatitis at A Tertiary Care Hospital.

Dr. Jayshri Pethani, Dr. Hitarthi Mehta, Dr. Komal Dholaria, Dr. Atit Shah, Dr. Bimal Chauhan, Dr. Lata Patel

Abstract :

Introduction: Hepatitis A virus(HAV) and Hepatitis E virus(HEV) are both enterically transmitted, resulting in acute viral hepatitis(AVH) in developing countries.

Methods: This study was done a record based at tertiary care hospital, Ahmedabad from January 2016 to December 2016 for the detection of HAV and HEV, using commercially available ELISA kits.

Results: Out of 1325 samples, 342 were positive for HAV, indicating a prevalence rate of 25.8%, majority patients were in the paediatric age group 1-10 years. In the case of HEV, 796 samples were positive indicating prevalence rate of 60%, majority patients were in adult age group 20-30 years. The seroprevalence of both HAV and HEV in patients with acute viral hepatitis was 4.22%, with 53.5% were males and 46.4% females.

Conclusion: This study shows a high prevalence of HEV than HAV. Prevalence was higher in adult and paediatric age group in case of HEV and HAV respectively and their co-infection rate was 4.22%.