A study of prevalence and association of peripheral neuropathy in Patients with newly diagnosed type 2 diabetes mellitus in a urban locality of Raipur district

Dr Shuddhodhan B Gaikwad; Dr. Jaiwant P Sachdev

Volume : VIII, Issue : IX, September - 2019

A study of prevalence and association of peripheral neuropathy in Patients with newly diagnosed type 2 diabetes mellitus in a urban locality of Raipur district

Dr Shuddhodhan B Gaikwad, Dr. Jaiwant P Sachdev

Abstract :

Introduction: Diabetes is one of the commonest non-communicable disease in India with its onset almost a decade earlier as compared to developed countries. Diabetic peripheral neuropathy (DPN) predisposes to foot ulceration and gangrene. Studies among recent onset patients with type 2 diabetes mellitus (T2DM) are very few. We studied the prevalence and risk factors of DPN in patients with newly diagnosed T2DM. Method: We studied 195 consecutive patients over age 30 with a duration of diabetes ≤6 months. All underwent a clinical and biochemical evaluation and were screened for DPN using Neuropathy Symptom Score (NSS) and Neuropathy Disability Score (NDS) as well as the viation perception threshold using a biothesiometer. Results: The overall prevalence of DPN was 29.% . PN among control was 10.7% . The prevalence of DPN showed an increasing trend with age . Abnormal viation perception threshold was present in 43.% of cases and had a significant correlation with NDS . Abnormal monofilament testing was present in 6.1% of cases. A regression analysis showed that DPN was independently associated with age and duration of diabetes prior to presentation but not with body mass index, plasma glucose, or HbA1c. Conclusion: Study showed high prevalence of PN in recently diagnosed patients with T2DM, which was independently associated with age and duration of symptoms of diabetes prior to the diagnosis. Screening for DPN at diagnosis of diabetes is warranted, especially among older subjects.