Volume : VI, Issue : III, March - 2017

A Study on Digitalization of Banks within India

Twinkle M. Trivedi

Abstract :

 The present study was designed to scientifically evaluate the cardiotonic activity of ethanolic extract of Brassica oleraceae L. var. italica (Family: Brassicaceae), against hydrogenated oil (dalda) induced myocardial ischemic in albino rats. Myocardial ischemia was produced in rats with 100 mg/kg of dalda administered orally in 50 days. Effect of oral treatment of ethanolic extract of Brassica oleraceae L. var. italica at a dose (250 mg/kg body weight), was given simultaneously for 50 days.  Ethanolic extract of this plant showed significant cardiotonic effect by lowering the serum levels of various biochemical parameters like Creatinine Phospho Kinase (CPK), Lactate Dehydrogenase (LDH), Alanine Amino Transferase (ALT) and Aspartate Amino Transferase (AST) were estimated in both the serum and heart tissues; antioxidant parameters viz., catalase (CAT) and malondialdehyde (MDA) were assayed in heart homogenate. The selected model in prophylactically and curatively manner was evaluated against dalda induced myocardial ischemia. The results also suggests that the biologically active phytoconstituents such as flavonoids, glycosides, alkaloids present in the ethanolic extract of plant which is confirmed from the qualitative analysis may be responsible for the significant cardiotonic activity. However, it suggests that a dose adjustment may be necessary to optimize the effects in clinical settings.

Keywords :

Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

V. RAMAMURTHY, K. DURGA DEVI, STUDIES ON ETHANOLIC EXTRACT OF BRASSICA OLERACEA L. VAR. ITALICA (BROCCOLI) AND THEIR EFFECT ON DALDA INDUCED ALBINO RATS, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-6, Issue-3, March‾2017


Number of Downloads : 554


References :