Anemia in Chronic Kidney Disease and Correlation of Serum Creatinine with Serum Ferritin Levels in the same group.

Dr. Archana Bembde; Dr. Shivani Joshi; Dr. Akshi Gupta; Dr. C.P. Bhale

Volume : IX, Issue : VIII, August - 2020

Anemia in Chronic Kidney Disease and Correlation of Serum Creatinine with Serum Ferritin Levels in the same group.

Dr. Archana Bembde, Dr. Shivani Joshi, Dr. Akshi Gupta, Dr. C. P. Bhale

Abstract :

Purpose: Anemia is a common complication associated with CKD (Chronic Kidney disease) that limits the quality of life and affects the morbidity and mortality in CKD patients. Mainstays for treatment of anemia are erythropoiesis stimulating agents (ESA) and Iron therapy. Serum ferritin, frequently used as a marker of iron stores in dialysis patients, is also an acute phase reactant, which could be used as a marker of morbidity and mortality in CKD patients. Thus, our aim is to study anemia in CKD patients who were on dialysis and receiving ESA and Iron therapy and to study the correlation between serum creatinine levels with serum ferritin levels in the same group. Methods & Results: The study was conducted on 150 indoor CKD patients and 150 control group. The following parameters were observed in the cases with mean values of: haemoglobin (9.11 � 2.54 g/dl), MCV (79.26 �14.23fl), MCH (26.36 � 7.16pg), MCHC (31.32 � 2.73g/dl), serum iron (45.02 � 50.40u/dl), TIBC (251.68 � 102.20u/dl), transferrin saturation (17.47 � 29.85%), serum ferritin (452.78 � 433.45ng/dl), serum creatinine (13.77�8.54mg/dl) and serum urea (105.25�55.98mg/dl). Conclusion: To conclude, the data analysis showed persistence of renal anemia with significant p value (<0.01) and there was a positive correlation of serum creatinine and serum ferritin levels (r value 0.98). Ferritin, being an acute phase reactant can thus be used as a marker of morbidity in CKD patients.