Volume : IX, Issue : VI, June - 2020

Assessment of efficacy of activated autologous platelet rich plasma therapy in chronic non-healing leg ulcers using percentage reduction in surface area and photographic

Dr Ilavendiran Sekar, Dr Brinda G David, Dr Roshni Menon

Abstract :

Introduction: Chronic non-healing leg ulcers are a misery for the patients and a challenge for the treating doctor. They pose considerable morbidity, financial and social burden on the affected person. The lack of response to conventional treatments makes it a difficult problem to tackle. Platelet rich plasma (PRP) has been a major eakthrough in the treatment of chronic non-healing ulcers as it provides various growth factors that enhance wound healing. The aim of our study was to evaluate the efficacy of activated autologous PRP in chronic non-healing leg ulcers of varying aetiologies. Methods: Activated autologous PRP was injected to the ulcer borders at definite intervals according to the protocol to 50 patients with chronic non-healing ulcers of varying aetiologies. Treatment outcome was assessed by percentage reduction in ulcer surface area and photographic wound assessment tool (PWAT) score. Results: Among 50 patients, 46% had diabetic ulcers, 28% had venous ulcers, 20% had leprosy ulcers and 6% had post traumatic ulcers. After PRP therapy, 76% of patients showed excellent response, while 8% patients showed good and 16% patients showed moderate response. None of the patients showed poor response. Conclusion: Autologous PRP is a safe and effective treatment modality for recalcitrant non-healing leg ulcers of varying aetiologies. However formulations of universal guidelines for preparation and administration of PRP may help in better treatment outcome.

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

ASSESSMENT OF EFFICACY OF ACTIVATED AUTOLOGOUS PLATELET RICH PLASMA THERAPY IN CHRONIC NON-HEALING LEG ULCERS USING PERCENTAGE REDUCTION IN SURFACE AREA AND PHOTOGRAPHIC, Dr Ilavendiran Sekar, Dr Brinda G David, Dr Roshni Menon GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-9 | Issue-6 | June-2020


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