ASSESSMENT OF RETINAL NERVE FIBRE LAYER THICKESS IN TYPE II DIABETIC PATIENTS WITHOUT DIABETIC RETINOPATHY BY OPTICAL COHERENCE TOMOGRAPHY

Dr. Sanjeevani Ambekar; Dr. Apurva Puranik

Volume : VII, Issue : II, February - 2018

ASSESSMENT OF RETINAL NERVE FIBRE LAYER THICKESS IN TYPE II DIABETIC PATIENTS WITHOUT DIABETIC RETINOPATHY BY OPTICAL COHERENCE TOMOGRAPHY

Dr. Sanjeevani Ambekar, Dr. Apurva Puranik

Abstract :

In diabetic retinopathy, neuronal loss occurs earlier than microvascular abnormalities. Loss of neuronal tissue will lead to a decrease in RNFL .Any loss of neuronal tissue will lead to a decrease in retinal thickness .. Optical Coherence Tomography (OCT) is the most precise method to measure RNFL. Objective assessment of RNFL will help in developing neuroprotective therapeutic regimens. so that in future, a preventive rather than interventional approach can be applied in its treatment.

AIM To assess RNFL thickness by OCT in type 2 diabetic patients without DR and compare it with healthy volunteers to detect any nerve fie loss. To correlate RNFL loss with Hb1Ac.

Material &Methods : This is a cross sectional ,observational, descriptive study done on 100 eyes of type 2 diabetic patients without DR and compared with healthy volunteers matched for age and sex

Results When avg RNFL thickness of cases was compared with controls significant correlation noted (p-value < 0.05). Significant correlation was also noted in superior, inferior nasal and temporal quadrants .(p-value < 0.05) .No significant correlation found between RNFL thickness and HB1Ac.

CONCLUSION RNFL thinning noted in Type II diabetes patients . Assessment of RNFL thickness can serve as an important tool for early detection and treatment of Retinopathy