Volume : VIII, Issue : XI, November - 2019

ASSOCIATION BETWEEN LYMPHOCYTE-MONOCYTE RATIO (LMR) AND NUMBER OF CORONARY ARTERY LESIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME

Miftahul Fadhly, Rahmad Isnanta, Zainal Safri

Abstract :

Introduction : Acute coronary syndrome (ACS) is a term used to describe the spectrum of thrombotic coronary artery disease.The basic disorder is atherosclerosis which will cause atheroma plaque.Inflammation has an important role in the process of atherosclerosis. Lower lymphocyte counts and higher monocytes show clinical importance in many cardiovascular conditions. Multivariate analysis showed that LMR was an independent predictor in groups with medium to high syntax scores Aim : To determine the relationship between LMR value and the number of coronary artery lesions in patients with Acute Coronary Syndrome Methods : This was an observational study of 88 consecutive ACS patients who came to Adam Malik General Hospital Medan, from July 2017 to July 2018. Evaluation of LMR value, blood tests, and coronary angiography were performed in each subject. The number of coronary artery lesions were assessed by Vessel Score. Furthermore, the calculated LMR values are associated with Vessel scores using Chi-Square analysis. Results : From 88 research subjects, there were 35 (39,8%) subjects with Simple Vessel Disease (SVD) and 53 (60,3%) subjects with Multi Vessel Disease (MVD).Based on the results of the ROC analysis, it was found that the LMR cut-off point value of the Vessel Score was 1,221 with a sensitivity of 91,4% and specificity of 79.2% with a significant strength (p <0.001). In the Chi-Square analysis, there was a significant relationship between LMR value and Vessel score (p <0.001). Conclusion : There is a significant relationship between LMR value and the number of coronary artery lesions in ACS patients.

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

ASSOCIATION BETWEEN LYMPHOCYTE-MONOCYTE RATIO (LMR) AND NUMBER OF CORONARY ARTERY LESIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME, Miftahul Fadhly, Rahmad Isnanta, Zainal Safri GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-8 | Issue-11 | November-2019


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