Volume : VI, Issue : I, January - 2017

CLINICOPATHOLOGICAL CORRELATION OF POLYCYSTIC OVARIAN SYNDROME AND INFERTILITY IN 100 INFERTILE FEMALE CASES

Sunita Poriya, Sonia Kundu, Bhetariya Bharat, Nandini J. Desai

Abstract :

 Infertility  is  considered  as  a  matter  of  inequality  and  social injustice,  along  with  a  major  health  problem.  Among  the  causes  for  female  infertility, polycystic  ovarian syndrome (PCOS)  is  the  most  common  cause  of  anovulatory  infertility,  being  found  in  ∼75%  of cases.  It affects approximately 5-10% of women of reproductive age group. With  the advancement  in  hormonal  assessment  techniques, endometrial  biopsy  and Ultrasonography,  PCOS   has  shown  a  remarkable  increase  in  its  incidence  in  recent years.   OBJECTIVES: To Diagnose the  cases of  PCOS   by using  triad of  ultrasonography ,biochemical investigations  like  LH, FSH  and  Prolactin  levels  and  endometrial  biopsy  and  thus  evaluating  the  correlation  of  PCOS  and  infertility  and  the  preferred  treatment  line.   MATERIAL  AND  METHODS:  This  was  a  study  of   100  infertile  females  ( excluding  the  male  factors)  over  a  period  of  two  years (2013-2015).  Evaluation  for PCOS  was  done  using  hormonal  assay,  ultrasonography  and  endometrial  biopsy  in  a tertiary  care  hospital. RESULT:  In  our  study,  ovulatory  defects  were seen in 37 cases (37%) which  constituted  maximum  number  of cases  in  female  infertility. PCOS  constituted  18 cases (48.6%) of  the  ovulatory  defects, maximum  in  the  age  group  of  26-30 years ( 38.9%),  among  which 72.2%  were  of primary  infertility  type.  LH:FSH  ratio  was  more  than  1.6  in  88.9%  of  the PCOS  cases. Maximum  PCOS  cases  were correlating  to  the  histopathological  finding  of  anovulatory  phase  of  endometrium  and  more  than  50%  were  correlating  with  ultrasonographic finding  of  PCOS ovary. CONCLUSION: PCOS was the most common   cause  of  infertility  among  young  females  of  new generation.  Combination  of  change  in  life  style  modifications  and  treatment  including clomiphene  citrate can  lead  to  better  outcome.

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

Sunita Poriya, Sonia Kundu, Bhetariya Bharat, Nandini J. Desai, CLINICOPATHOLOGICAL CORRELATION OF POLYCYSTIC OVARIAN SYNDROME AND INFERTILITY IN 100 INFERTILE FEMALE CASES, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-6, Issue-1, January‾2017


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