CLINICOPATHOLOGICAL PROFILE OF ENDOMETRIAL HYPERPLASIA AND   ENDOMETRIAL CARCINOMA

Shivani Mishra; Uma Singh; Sabuhi Quereshi; Prachi Srivastava; Madhumati Goel

Volume : V, Issue : III, March - 2016

CLINICOPATHOLOGICAL PROFILE OF ENDOMETRIAL HYPERPLASIA AND ENDOMETRIAL CARCINOMA

Shivani Mishra, Uma Singh, Sabuhi Quereshi, Prachi Srivastava, Madhumati Goel

Abstract :

Endometrial carcinoma is the most common malignancy of female genital tract. Recently, EIN scheme has been adopted as an alternative to WHO classification. This study was planned to study the clinicopathological profile of cases with endometrial hyperplasia and endometrial carcinoma and to study EIN in cases with endometrial hyperplasia. 168 premenopausal and postmenopausal women > 40 years of age with abnormal uterine bleeding were included in the study. Women with coagulopathy, iatrogenic bleeding per vaginum, malignancy other than endometrial carcinoma and those not willing to participate were excluded from the study. Present study showed endometrial carcinoma to be strongly associated with age, menopausal status, BMI, diabetes, hypertension and postmenopausal bleeding. Out of 50 cases diagnosed with endometrial hyperplasia, 4 cases were positive for EIN. EIN system can be used to represent these cases as it predicts disease progression more accurately than WHO-94 classification.