Comparison of antimicrobial efficacy of Liquorice and Sodium hypochlorite against Staphylococcus aureus.

Sumit Rajewar; Arunkumar Sajjanar; Sadanand Kulkarni; Manveen Lamba; Priyanka Gupta; Pratima Kolekar

Volume : IX, Issue : VI, June - 2020

Comparison of antimicrobial efficacy of Liquorice and Sodium hypochlorite against Staphylococcus aureus.

Sumit Rajewar, Arunkumar Sajjanar, Sadanand Kulkarni, Manveen Lamba, Priyanka Gupta, Pratima Kolekar

Abstract :

Aim-To compare the antimicrobial efficacy of liquorice and sodium hypochlorite against staphylococcus aureus. Materials and method- The present study was conducted in the Department of Pediatrics and preventive dentistry, Swargiya Dadasaheb Kalmegh Smruti Dental College Nagpur, in collaboration with Department of Microbiology. Ethical clearance for the trial was obtained from the Institutional Ethics Committee of Swargiya Dadasaheb Kalmegh Smruti Dental College. Liquorice roots were obtained from herbal medical shop in Nagpur Maharashtra. Liquorice roots were dried in shade and coarse ground were made with the electric blender. Sample of the powder were soaked in distilled water for 24 h with intermittent shaking. The active ingredients leached out in the solvent were subsequently filtered using several folds of muslin cloth and Whatman No. 1 filter paper. The filtrate of extract was concentrated using a rotavapor and freeze dried using lyophilization, following which the residues were finely ground, weighed, and stored at 4�C for further experiments. Results- At the end of 48hr, statistically significant anti-microbial activity was demonstrated by 50% Liquorice extract and 3% Sodium Hypochlorite used in this study (P = 0.002). Conclusion- The inhibitory effect shown by 50% Liquorice extract against Staphylococcus aureus was superior when compared with that of 3% Sodium Hypochlorite.