Comparison of maintenance and recovery characteristics with isoflurane or sevoflurane for ambulatory anaesthesia

Dr. Mukesh Kumar; Dr.Harish Kumar; Dr. Ekramul Haque

Volume : VII, Issue : VI, June - 2018

Comparison of maintenance and recovery characteristics with isoflurane or sevoflurane for ambulatory anaesthesia

Dr. Mukesh Kumar, Dr. Harish Kumar, Dr. Ekramul Haque

Abstract :

Introduction:Surgery is increasingly performed on a day-case basis. An ideal day-care anaesthetic agent should have rapid smooth induction, provide optimum surgical conditions with rapid recovery and minimal side effects. In recent times, inhalational agents like isoflurane and sevoflurane have shown a promising result for such type of surgeries.

Aim &objectives:this randomized double blind study was designedto compare isoflurane and sevoflurane during short surgical procedure regardingIntraoperative haemodynamic stabilityRecovery profile and Adverse effects.

Method: : 60 patients ASA 1 AND 2were randomly divided into two groups including 30 patients.Group I: Patients who maintained on isoflurane anaesthesia

Group S: Patients who maintained on sevoflurane anaesthesia.All patients were monitored with pulseoximeter for SpO2, HR and RR.Vitals were recorded before pre-medication, The volatile agent was administered at approximately one �minimal alveolar concentration� (MAC) for 3 min i.e. 1.2% for isoflurane and 2% for sevoflurane. Then it continued at 0.75 MAC i.e. 0.8% for isoflurane and 1.5% for sevoflurane, further increasing or decreasing by 0.5% for sevoflurane and 0.2% for isoflurane (0.5 MAC) according to the clinical assessment. At the end of surgery, administration of isoflurane or sevoflurane discontinued without tapering.The Hemodynamic parameters, Emergence time, adverse effect (PONV, pain, airway hyper reactivity) and discharge time from PACU & for home were recorded.

Result:The use of sevoflurane resulted in quicker emergence and faster early recovery.The mean arterial pressure was lower from baseline in both groups after induction. Isoflurane has more incidence of airway hyper reactivity though milder when compared to sevoflurane.

Conclusion: Sevoflurane may be a useful inhaled anesthetic for maintenance of adult ambulatory anaesthesia.