EFFECT OF INJ. ESMOLOL AND INJ. FENTANYL ON HAEMODYNAMIC CHANGES DURING LARYNGOSCOPY &TRACHEAL INTUBATION- A COMPARATIVE STUDY

DR ABHAY RAJ YADAV; DR NEELESH NEMA; DR ADITYA AGARWAL

Volume : VII, Issue : IV, April - 2018

EFFECT OF INJ. ESMOLOL AND INJ. FENTANYL ON HAEMODYNAMIC CHANGES DURING LARYNGOSCOPY &TRACHEAL INTUBATION- A COMPARATIVE STUDY

Dr Abhay Raj Yadav, Dr Neelesh Nema, Dr Aditya Agarwal

Abstract :

Aim and objectives:

1) To evaluate the effects of Esmolol and Fentanylon haemodynamic changes during Laryngoscopy and tracheal intubation.

2) To compare the effect of Esmolol and Fentanylonhaemodynamic changes during Laryngoscopy and tracheal intubation.

3) To compare the side effects.

Materials & Methods

This prospective observational study was conducted on 80 patients of ASA Grade I &II , undergoing elective surgeries under general anesthesia.

GroupA:Injection Esmolol 2 mg/kg i.v. 3 min before laryngoscopy andintubation, over 30 seconds.

Group B;Injection Fentanyl 2 μg/kg i.v. 3 min before laryngoscopy andintubation, over 30 seconds.

All patient received Inj. Pentazocine 0.3mg/kg and were pre-oxygenated for 3min. Anaesthesia was induced with thiopantone sodium (5mg/kg IV) till loss of eyelashreflex over 30 second and mask ventilation was confirmed. Injsucchinylcholine 1.5mg/kg was given to facilitate laryngoscopy and intubation. anaesthesia was maintained with oxygen nitrous oxide ,halothane with intermittent use of inj. Atracurium and controlled ventilation.

At the end of surgery the neuromuscular blockade was antagonized with inj. Glycopyrolate (.01mg/kg)I.V.and inj. Neostigmine(.05mg/kg)i.v. and patient were extubated.

RESULT

Esmolol is more effective than Fentanyl in attenuation of haemodynamic changes during laryngoscopy and intubation.

CONCLUSION

Esmolol significantly attenuates the haemodynamic changes during laryngoscopy and intubation. Fentanyl also significantly attenuates the haemodynamic changes during laryngoscopy and intubation.Thus we conclude that Esmololis a better drug to attenuate the haemodynamic response during laryngoscopy and intubation.