Efficacy of Vitamin D3 supplementation in diabetic children: a cohort prospective study

S A Karina; P Winra; S A Nindia

Volume : IX, Issue : III, March - 2020

Efficacy of Vitamin D3 supplementation in diabetic children: a cohort prospective study

S A Karina, P Winra, S A Nindia

Abstract :

Diabetes mellitus (DM) is a complex metabolic disorder characterized by chronic hyperglycemia due to defect from insulin secretion, insulin action, or both. Despite intensive diabetes management, less than a fifth of diabetic patients achieve the recommended HbA1c target. This cohort prospective design study was conducted in the pediatric endocrinology division of Haji Adam Malik Hospital Medan from March- October 2019. A total of 14 children were enrolled in this study. This study result showed increase of 25(OH)D level from 18.6�5.6ng/mL to 27.3�5.9ng/mL (p=0.00) and decrease of HbA1c level from 9.8%�1.9 to 7,0%�1.1 (p=0.00). This study found a negative correlation between the HbA1c value and 25(OH)D level (r-0.83;p=0.00). The management of DM with standard medication plus vitamin D supplementation showed a satisfactory result and is expected to become a routine recommendation in the management of children with DM.