Elevated Levels of Acid Phosphatase in Patients of Malaria with Respect to Types of Malaria and Parasitic Index

Dr.Sneha Wadalkar; Dr.Vinita Singh; Dr.Samir Pachpute; Dr.A.D.Deepak

Volume : VIII, Issue : IV, April - 2019

Elevated Levels of Acid Phosphatase in Patients of Malaria with Respect to Types of Malaria and Parasitic Index

Dr. Sneha Wadalkar, Dr. Vinita Singh, Dr. Samir Pachpute, Dr. A. D. Deepak

Abstract :

Malaria is one of the most prevalent parasitic disease. Acid phosphatase enzyme releases during erythrocytic phase of life cycle of malarial parasite. Acid phosphatase can act as a marker for Malaria as well as marker to assess severity of hemolysis in cases of Malaria. Objectives: To estimate serum Acid phosphatase levels and haemoglobin levels in patients of Malaria and control subjects. Material and methods: Collected 5 ml Blood from healthy individuals and patients of Malaria was divided in plane vacutainer and EDTA vacutainer for serum ACP and haemoglobin respectively.Blood Haemoglobin levels were analysed by Drapkin�s Method. Serum Acid phosphatase levels were analyzed by Teco diagnostic kit. Result: Acid phosphatase levels were significantly higher in study group (5.9 � 1.4 U/L) compared to control group(p<0.001). Negative correlation obtained between ACP and blood Hb, r = -0.692. Conclusion – Enzyme ACP can be used as an Additional diagnostic marker in Malaria to the routine tests.