Volume : VI, Issue : IV, April - 2017

Evaluation of plasma fibrinogen levels in diabetes mellitus and its correlation with HbA1c levels.

Metan Sb

Abstract :

 Background Diabetes mellitus comprises a group of common metabolic disorder where increased fiinogen level can act as a thrombogenic factor. Diabetic patients have higher cardiovascular morbidity than non diabetic subjects. Several studies have shown that haemostatic  factor especially hyperfiinogenaemia is implicated as a source of atherosclerosis. Material and method : A  study was conducted to compare fiinogen levels between 30 type 2 diabetes patients and 10 age and sex matched healthy controls. Their  fiinogen levels are compared and correlated with  risk factors like glycosylated  haemoglobin ,age ,sex ,smoking ,body mass index(kg/m2),and hypertension. Results : It was seen that in diabetic patients ,the plasma fiinogen levels were higher than non diabetic even though it was not statistically significant.(327.37 ±47.25 vs 327.1±72.45: p > 0.05) . The study re established co relation between HbA1c  and fiinogen levels of the diabetic patient is positive i.e.,poorer the glycaemic status ,higher the fiinogen levels .(r=0.21). Conclusion :  It can be concluded that fiinogen levels are increased in diabetic subjects which is associated with glycemic index .This contributes to the excess cardiovascular morbidity and mortality.

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

Metan SB, Evaluation of plasma fibrinogen levels in diabetes mellitus and its correlation with HbA1c levels., GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-6, Issue-4, April‾2017


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