Volume : VI, Issue : II, February - 2017

EXPRESSION OF ESTROGEN AND PROGESTERONE RECEPTORS IN BREAST CARCINOMA

Dr. Navyaa. V. R, Dr. Ramkishan. G

Abstract :

 Background: Breast carcinoma is the most common malignant tumor and the leading cause of death in women worldwide. Of the various parameters, expression of hormone receptors in particular estrogen receptor(ER) and progesterone receptor (PR) is significant. Study design: 50 cases of proven east carcinoma diagnosed in the Department of Pathology, Katuri Medical College and Hospital, Guntur from October 2013 to October 2015 which includes 50 prospective cases. Results: In the present study 70% expressed estrogen receptors and 64 expressed progesterone receptors.  Of 50 cases, 64%  were ER+/PR+, 6% were ER+/PR- and remaining 30%  were ER-/PR-. Histological grading in correlation with ER/PR positivity was found to be statistically significant (p <0.001).  Conclusion: Prognosis and management of east cancer are influenced by classic variables such as histological type and grade, tumor size, lymph node status, status of hormone receptors- ER and PR. 

Keywords :

Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

Dr. NAVYAA.V.R, Dr. RAMKISHAN. G, EXPRESSION OF ESTROGEN AND PROGESTERONE RECEPTORS IN BREAST CARCINOMA, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-6, Issue-2, February‾2017

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