Histomorphometric analysis of Umbilical Cord in Gestational Diabetes Mellitus

Amit Jain; Rajiv Ranjan; Rashmi Bhujade

Volume : VI, Issue : VII, July - 2017

Histomorphometric analysis of Umbilical Cord in Gestational Diabetes Mellitus

Amit Jain, Rajiv Ranjan, Rashmi Bhujade

Abstract :

Aim: The aim of present study was to determine the adverse effects of gestational diabetes on the histomorphological features of the umbilical cord.

Place of study: Department of Anatomy, R.D.Gardi Medical College, Ujjain

Materials and Methods: Total 100 umbilical cords with the placenta were examined. The relevant data were collected from patients delivered in C.R. Gardi hospital,Ujjain within 36th to 40th weeks of gestation. Control cords (n = 50) were from healthy women whose pregnancies were not complicated by any major disease. GDM cords (n = 50) were from mothers with gestational diabetes mellitus (GDM group). All the placentas with cords were treated identically in a standard manner. All placentas were fixed in 10% buffered formalin for 2 weeks. The diameter of the umbilical cord was measured in millimeters and the Circumference, the Cross-Sectional Area of the umbilical cord and Cross-Sectional Area of the Wharton�s jelly were measured in millimeters and sq. millimeters respectively.

Result: The study demonstrated that in GDM group the mean diameter, the mean circumference, the mean CSA of the umbilical cord and the mean CSA of the Wharton�s jelly were larger in the GDM group than the Control group. The difference was significant in case of the mean diameter while it did not reach to the significant level for the other parameters.