Volume : V, Issue : XI, November - 2016

McCune Albright Syndrome: A Case Report & Review of Literature

Richard Mario Lurshay, Pramod Paharia, Santanu Deb, Indrani Roy, Sabrina Yesmin

Abstract :

 McCune Alight syndrome (MAS) is characterized by the classical triad of polyostotic fious dysplasia (FD), skin hyperpigmentation (café-au-lait spots), and endocrine dysfunction. We report a 21 month girl with MAS, who presented with vaginal bleeding and recurrent fractures. Physical examination revealed multiple café-au-lait spots and features of advanced east development for age. What makes this case unusual was the radiography findings of polyostotic fious dysplasia in all the long bones and skull, an unusually early feature in this child. Ultrasonography revealed bilateral ovarian cysts with a bulky uterus. Hormonal studies revealed very high estradiol levels, as well as elevated serum levels of progesterone, prolactin, adrenocorticotrophic (ACTH), free thyroxine (FT4) and triiodothyronine (FT3). Severe deficiency of Vitamin D was also noted.

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

Richard Mario Lurshay, Pramod Paharia, Santanu Deb, Indrani Roy, Sabrina Yesmin, McCune Albright Syndrome: A Case Report & Review of Literature, Global Journal For Research Analysis,Volume : 5 | Issue : 11 | November 2016

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