Pattern of Lipid Profile in Type-2 Diabetic Subjects: An Obervational and Cross Sectional Study

Dr. Kalpen Patel; Dr. Arpit Gohel; Dr. Prashant Jadav

Volume : VII, Issue : IX, September - 2018

Pattern of Lipid Profile in Type-2 Diabetic Subjects: An Obervational and Cross Sectional Study

Dr. Kalpen Patel, Dr. Arpit Gohel, Dr. Prashant Jadav

Abstract :

Introduction: Type 2 diabetes mellitus (T2DM) is one of the most widespread forms of DM characterized by hyperglycemia, insulin resistance, and relative insulin deficiency. Dyslipidemia in diabetes commonly manifests as raised low-density lipoprotein cholesterol (LDL-C), decreased high-density lipoprotein cholesterol (HDL-C) levels, or elevated triglyceride (TG) levels.Material and methods: This is an observation and cross sectional study was planned to analyze the pattern of dyslipidemia in diabetic patients attending the GCS Medical College, Hospital and research Center, Asarwa, Ahmedabad. The study comprised of 100 subjects. They were divided into two groups, 50 subjects with DM and 50 control without DM over the span of four months (December 2014 to March 2015). FBS PPBS and Lipid profile were performed in cases and controls using appropriate tests. The data was analyzed with SPSS version 22.0. The mean, SD, independent t test and correlation (Pearson�s) test were used to interpret the results. Results: There was highly significant difference in mean HDL in diabetic patients(45.2�10.8) and controls(53.2�6.5) (p<0.0001). Also a highly significant difference was found in mean triglyceride in diabetic patients (145.3�73.4) and controls(93.3�64.5) (p<0.0001). There was statistically significant correlation found between study and control groups for LDL,VLDL . Conclusion: The study demonstrated the typical diabetic dyslipidemia which is characterized by low HDL, high triglyceride and high cholesterol. LDL and VLDL were also raised. The important impact of dyslipidemia on cardio vascular complications requires undivided attention throughout the course of disease.