Volume : VII, Issue : IX, September - 2018

Pregnancy-Associated Atypical Hemolytic-Uremic Syndrome

Dr. Sonam Jadhav, Dr. Shaifali Patil

Abstract :

Pregnancy is associated with various forms of thrombotic microangiopathy, including hemolytic uremic syndrome. Atypical haemolytic uraemic syndrome is one of the main variants of thrombotic microangiopathy, and is characterised by excessive complement activation in the microvasculature. Pregnancy-associated atypical hemolytic-uremic syndrome (p-aHUS) is a rare condition characterized by microangiopathichemolyticanemia, thrombocytopenia, and acute kidney injury. Triggered by pregnancy, genetically predisposed women develop the syndrome, leading to a disastrous hemolytic disease characterized by diffuse endothelial damage and platelet consumption [1].

Being one of the differential diagnoses of preeclampsia–eclampsia andHELLP syndrome the clinician must be familiar with the disease due to its high mortality, which can be modified with early diagnosis and comprehensive treatment. The authors have here reported a case of atypical haemolytic uremic syndrome diagnosed postnatal.

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

Dr. Sonam Jadhav, Dr. Shaifali Patil, Pregnancy-Associated Atypical Hemolytic-Uremic Syndrome, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-7 | Issue-9 | September-2018


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