PREVALENCE OF THYROID DYSFUNCTIONS IN TYPE 1 DM, TYPE 2 DM, LOW BODY WEIGHT TYPE 2 DM AND GDM PATIENTS IN BUNDELKHAND REGION- A HOSPITAL BASED STUDY IN MAHARANI LAXMI BAI MEDICAL COLLEGE, JHANSI

Dr. Mandavi Agarwal; Dr. Ram Diwakar; Dr. Lakhan Singh; Dr. Arun Verma; Dr. Ragini Singh

Volume : IX, Issue : IV, April - 2020

PREVALENCE OF THYROID DYSFUNCTIONS IN TYPE 1 DM, TYPE 2 DM, LOW BODY WEIGHT TYPE 2 DM AND GDM PATIENTS IN BUNDELKHAND REGION- A HOSPITAL BASED STUDY IN MAHARANI LAXMI BAI MEDICAL COLLEGE, JHANSI

Dr. Mandavi Agarwal, Dr. Ram Diwakar, Dr. Lakhan Singh, Dr. Arun Verma, Dr. Ragini Singh

Abstract :

Background: DM and thyroid disorders mutually influence each other so excess or deficiency of one can result in functional derangement of other. Material and Method: This was a prospective observational study of thyroid dysfunction in diabetic patients over a period of 1.5 years: Biochemical markers of diabetes and thyroid dysfunction, namely HbA1c, PPBS, FBS, FT4 and TSH were measured in all patients. Results: A total 120 patients of different type of DM were studied. In our study most of cases was type-II DM (41.6%), followed by LBW type II DM (25%), DM Type 1 (25%) and 8.3% of GDM. Most of the cases were male (54.16%) and rest cases were female. Most of cases were in age group of 41 to 60 year of age (50%) followed by 21 to 40 (26%), 61-80 (22%). In our study more thyroid dysfunction was found in diabetic patients (32.6%) in comparison to non diabetic (16%), among which subclinical hypothyroidism (19.17%) more common than hypothyroidism and hyperthyroidism (4.16%). Patients with type I DM had more prevalence of thyroid dysfunction (43.33%) followed by DM type II (36%) and LBW DM type II (23. 3%) in comparison to control (16%) and in all type of diabetics, sub clinical hypothyroidism was more prevalent. Among diabetic subjects with SCH and hypothyroidism had proportion of dyslipidemia, hypercholesterolemia (47.82% and 63.63% versus 25.93%) in comparison to euthyroid patients. Similarly for hyper triglyceridemia (43.48% and 81.82% versus 32%) and for increase LDL (26.08% and 54.55% versus 14.81%). In our study, the subject with duration of diabetes of 6 month to 5 years and more than 5 years had higher prevalence SCH (43.8% and 47.83 Versus 8.70%) in comparison to <6 month of duration. Similarly for hypothyroidism (27.27% and 54.55% versus 18.18%). Conclusion: Thyroid dysfunction is more prevalent in diabetics in comparison to normal population in which type I had more prevalent followed by type II DM and LBW type II DM. Patients having thyroid dysfunctions also have dyslipidemia and as the duration of diabetes increases, prevalence of thyroid dysfunction increases.