Primary Pulmonary Nodular Amyloidosis With Co-existing Microfilarial Infestation: A Case Report

Ashwini Sangvikar; Rakesh Shedge; Vikas Kavishwar; Gayathri Amonkar

Volume : VIII, Issue : V, May - 2019

Primary Pulmonary Nodular Amyloidosis With Co-existing Microfilarial Infestation: A Case Report

Ashwini Sangvikar, Rakesh Shedge, Vikas Kavishwar, Gayathri Amonkar

Abstract :

Primary pulmonary amyloidosis is a rare disease characterized by the deposition of congophilic amyloid fiils in extracellular tissue. The term �amyloid� was coined by Rudolph Virchow in 1854. It is can be hereditary or acquired, localized or systemic and potentially lethal or merely an incidental finding. Amyloidosis in lung was first recognized by Lesser in 1877. It can be primary or secondary to various hereditary, inflammatory or neoplastic pathogenesis. Till date, there are 27 known extracellular fiil proteins identified in humans. The extracellular deposits interfere with organ functions and may lead to death. The most common presentations of amyloidosis are unexplained nephrotic syndrome, cardiomyopathy. Primary pulmonary nodular amyloidosis should be considered in the differential diagnosis of pulmonary nodules or masses. Here we are presenting a case of coexistence of primary pulmonary nodular amyloidosis with microflarial infestation.