PROSPECTING ANTIMCROBIAL POTENTIAL OF Tinospora cordifolia (Thunb.) Miers. AND ITS PHYTOCHEMICAL EVALUATION

Velmurugan C; Arulkumar M; E.G. Wesely; MD Nazneen Bobby; Nathan Vinod Kumar

Volume : VI, Issue : V, May - 2017

PROSPECTING ANTIMCROBIAL POTENTIAL OF Tinospora cordifolia (Thunb.) Miers. AND ITS PHYTOCHEMICAL EVALUATION

Velmurugan C, Arulkumar M, E. G. Wesely, Md Nazneen Bobby, Nathan Vinod Kumar

Abstract :

Tinospora cordifolia., is shrub of the Family Menispermaceae which is used in many traditional medicines. It is rich in many phytochemicals like flavanoids, alkaloids, tanins etc. The bio potential of some parts was not explored. In the present work, we investigate the preliminary phytochemicals of chloroform extract of leaf and stem. The antimicrobial efficacy of these extract against selected microorganisms namely against E.coli, Pseudomonas aeruginosa, Bacillus subtilis and Salmonella typhi were evaluated. Similarly, antifungal activity was also evaluated against selected fungal strains. The leaf and stem extracts were found very significantly inhibiting E.coli at the highest concentrations very effectively. The extract also inhibited growth of Aspergillus and Rhizopus sp. These extracts were efficiently inhibiting the multidrug resistant pathogenic strains. The phytochemical analysis revealed that the extract contained alkaloids, tannins, terpenoids etc. which may be attributed to the antimicrobial effect of the extract. The chloroform extract of the T.cordifolia was less explored for its bio-potential and hence the work is a preliminary report with significant findings of its bio-potential. < clear="all" style="page-eak-before:always;mso-eak-type:section-eak" />