ROLE OF BONE MARROW ASPIRATION AND TREPHINE BIOPSY IN THE DIAGNOSIS OF VARIOUS BONE MARROW PATHOLOGY ESPECIALLY HEMATOPOIETIC DISORDERS.

Rashmi Sharma; Geeta Pachori; Akhilesh Bharadwaj; Supriya Singh Toor

Volume : VI, Issue : XI, November - 2017

ROLE OF BONE MARROW ASPIRATION AND TREPHINE BIOPSY IN THE DIAGNOSIS OF VARIOUS BONE MARROW PATHOLOGY ESPECIALLY HEMATOPOIETIC DISORDERS.

Rashmi Sharma, Geeta Pachori, Akhilesh Bharadwaj, Supriya Singh Toor

Abstract :

Bone marrow is frequently involved in various pathologies, especially hematological disorders ,which are diagnosed by two interrelated techniques, bone marrow aspiration (BMA) and bone marrow biopsies (BMB).

AIM – To establish BMA and BMB as a simple, safe and relatively painless outdoor procedure, and to assess the diagnostic value of both when done simultaneously.

Methods –BMA and BMB was performed and morphological examination of bone marrow along with cytochemical staining was done and diagnostic value of bone marrow examination was established.

Result - Present study was done in 72 cases. The most common incidence was that of leukemias, 38 cases (52.78%),followed by 24 cases of anemias (33.33%) ,seven cases (9.72%) were of pancytopenia, two cases (2.78%) were of multiple myeloma and one case (1.39%) was of idiopathic thrombocytopenic purpura.

Conclusion- Morphological examination of bone marrow is an extremely helpful and specific diagnosic tool. BMA gives better morphology of the cell and BMB gives a good picture regarding the pattern of distribution of cells and the architecture in bone marrow