ROLE OF SINGLE DOSE OF INTRAVITREAL RANIBIZUMAB IN RETINITIS PIGMENTOSA ASSOCIATED CYSTOID MACULAR EDEMA--- A RETROSPECTIVE STUDY.

Dr. Kaushik Sadhukhan; Dr. Subhrajyoti Naskar; Dr. Dhritashree Mandal

Volume : VIII, Issue : V, May - 2019

ROLE OF SINGLE DOSE OF INTRAVITREAL RANIBIZUMAB IN RETINITIS PIGMENTOSA ASSOCIATED CYSTOID MACULAR EDEMA--- A RETROSPECTIVE STUDY.

Dr. Kaushik Sadhukhan, Dr. Subhrajyoti Naskar, Dr. Dhritashree Mandal

Abstract :

Purpose: To study the effect of single dose of intravitreal Ranibizumab(0.5mg) under topical anaesthesia in cystoid macular edema(CME) associated with Retinitis pigmentosa(R.P) over the period of 6 months. Methodology: 11 eyes of 11 patients with cystoid macular edema associated with Retinitis pigmentosa were taken into our study. After detailed history taking and detailed systemic and ocular examinations and spectral domain OCT to measure central macular thickness(CMT), prior informed consent and institutional clearance, we have administered single dose of intravitreal Ranibizumab(0.5mg) under topical anaesthesia to each patient. There after CMT was measured after 1month, 3 months, 6 months of injection respectively. Then we have used paired T test (with the help of SPSS software) to get the required statistical data. This is hospital based experimental uncontrolled clinical trial. Conclusion: Intravitreal Ranibizumab may be an effective tool to deal with RP-CME for the duaration of few months but prospective trials of longer duration are definitely needed to achieve concrete conclusion.