Volume : IX, Issue : V, May - 2020

Serum Ferritin Levels: A Potential Biomarker in Liver Cirrhosis Patients

Dr. Huma Nasrat, Dr. Amit Singh Ray, Dr. Tripti Saxena

Abstract :

Background: Liver cirrhosis and the child-Turcotte-Pugh (CTP) score are closely associated entities. CTP score is called as the mortality and prognosis predictor. Although, Ferritin emerges as a potential biomarker related to prognosis. To study that ferritin could be used as a prognostic marker in liver cirrhosis patients. Methods: The study analyzed 54 cirrhotic patients including 17 females and 37 males at Gandhi medical college and Hamidia hospital,Bhopal,Madhya-Pradesh between May 2018 and December 2019. Ferritin levels were, then, divided into trichotomous cut-off value (< 200 ng/mL, n = 22; 200–400 ng/mL, n = 5; and > 400 ng/mL, n= 27). Data was analyzed using SPSS version 12.0 (continuous variables were assessed by the Kruskal-Wallis test and Chi-square test was used for categorical variables). In addition, Spearman correlation test was used to determine any significant correlation between ferritin levels and CTP score. Results: Based on data analysis, gender and CTP score were related to higher ferritin levels (P= 0.002 and P = 0.018, respectively). Furthermore, a significant correlation between serum ferritin levels and CTP score was obtained in to moderate degree (P= 0.000;r= 0.487). Conclusions: There might be a significant role of serum ferritin levels in predicting mortality and prognosis among cirrhosis patients but it still needs further attention.

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

SERUM FERRITIN LEVELS: A POTENTIAL BIOMARKER IN LIVER CIRRHOSIS PATIENTS, Dr. Huma Nasrat, Dr. Amit Singh Ray, Dr. Tripti saxena GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-9 | Issue-5 | May-2020


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