STATUS OF SERUM CALCIUM AND VITAMIN-D LEVEL IN HYPOTHYROIDISM IN ONE OF THE RURAL AREA OF CENTRAL MAHARASHTRA

Yogita Dubey; Archana Dhok; Ruchir Khare

Volume : VII, Issue : VIII, August - 2018

STATUS OF SERUM CALCIUM AND VITAMIN-D LEVEL IN HYPOTHYROIDISM IN ONE OF THE RURAL AREA OF CENTRAL MAHARASHTRA

Yogita Dubey, Archana Dhok, Ruchir Khare

Abstract :

Introduction: Thyroid gland disorders are very common among endocrine diseases and incidence and prevalence increase with age but also affect younger age group. Thyroid disorders have direct and indirect effect on mineral metabolism. Peoples from rural area have lack of knowledge and awareness regarding thyroid disorders and its impact on calcium and Vitamin D status.

Aim & objectives: To evaluate status of serum Calcium and Vitamin D level in patients of hypothyroidism according to age and gender in rural area.

Material & methods: This prospective case control study was conducted in Department of Biochemistry, JNMC, Sawangi, Wardha in patients of hypothyroidism after obtaining informed consent.Study group comprises of 100 subjects. 50 cases of hypothyroidism of age group of 30 – 60 yrs both male and female and 50 controls of normal healthy persons same age and sex, from general population.

Results & Observations: The values of T3 and T4 were significantly lower in cases as compared to controls while TSH values were significantly high in cases as compared to control. Calcium and Vitamin D levels were also significantly low in cases.

Conclusions: Severity of vitamin D deficiency corresponds to the severity of thyroid disease, with progressive increase in TSH level from subclinical to overt hypothyroidism. Thus it may be suggested that vitamin D be supplemented to all hypothyroid patients including the subclinical cases.