STUDY OF SERUM Ig A CONCENTRATION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND CONTROL

Dr. Deepa V Sommanek; Dr. Jyoti G Chawda; Dr. Dhvani Mukeshkumar Patel; Dr. Mrudu J Gondalia; Dr. Dhara Z Mistry

Volume : VI, Issue : VIII, August - 2017

STUDY OF SERUM Ig A CONCENTRATION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND CONTROL

Dr. Deepa V Sommanek, Dr. Jyoti G Chawda, Dr. Dhvani Mukeshkumar Patel, Dr. Mrudu J Gondalia, Dr. Dhara Z Mistry

Abstract :

Diabetes Mellitus (DM) is a disease of absolute or relative insulin deficiency characterized by insufficient secretion of insulin by the pancreatic beta cells (type I) or decreased tissue response to insulin (type II). In diabetes, there is proliferation and swelling of endothelial cells, frequently obliterating the vessel lumen which leads to reduced blood flow and decrease in oxygen diffusion leads to good environment for the growth of microorganisms. The present study was carried out to evaluate the humoral immune status of controlled and uncontrolled type II diabetic patients by measuring the level of Serum Immunoglobulin A (Serum Ig A). For that blood samples from 7 controlled diabetes and 8 uncontrolled diabetes of type 2 were collected for measuring FBS, PPBS, Serum Ig A, Serum Creatinine, Blood Urea, Serum Sodium and Serum Potassium. Serum Ig A level was statistically significant in uncontrolled diabetes patients than controlled diabetes. So we can conclude that Serum Ig A is an important clinical parameter for monitoring diabetes and evaluating its secondary effects