Volume : VI, Issue : II, February - 2017

THE STUDY OF OXIDANT & ANTIOXIDANT STATUS IN NEPHROTIC SYNDROME

Dr. Jyoti Dwivedi, Dr. Ravinder Arora, Dr. Purnima D. Sarkar

Abstract :

 Nephrotic syndrome is a clinical syndrome caused by the increased permeability of the glomerular capillary wall for macromolecules. Peroxidation of lipid memanes raises the concentration of their by product MDA and the consequent lowering of antioxidants as a result of consumption. Therefore, this study was carried out to investigate oxidant and antioxidant status in nephrotic syndrome patients. The blood samples were analyzed for quantitation of malondialdehyde as index of lipid peroxide, total antioxidant capacity, homocysteine and lipoprotein (a). Significantly increased levels of serum lipid peroxide, homocysteine and decreased levels of serum total antioxidant capacity were noticed in the patients with nephrotic syndrome as compared to control subjects. However, significant positive correlation in lipid peroxide with homocysteine and negatively correlated with total antioxidant capacity were observed.

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

Dr.Jyoti Dwivedi, Dr.Ravinder Arora, Dr.Purnima D. Sarkar, THE STUDY OF OXIDANT & ANTIOXIDANT STATUS IN NEPHROTIC SYNDROME, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-6, Issue-2, February‾2017


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