To study distribution and antibiotic susceptibility pattern of Escherichia coli from various clinical samples at a tertiary care teaching hospital, in Solapur, Maharashtra

Dr Anu Sharma; Dr Akanksha Shatrughan Bali; Dr N.K. Shaikh

Volume : VII, Issue : XI, November - 2018

To study distribution and antibiotic susceptibility pattern of Escherichia coli from various clinical samples at a tertiary care teaching hospital, in Solapur, Maharashtra

Dr Anu Sharma, Dr Akanksha Shatrughan Bali, Dr N. K. Shaikh

Abstract :

Escherichia coli (E.coli) is one of the leading cause of UTI, and many other infections seen in humans, over the years due to increase rate of antimicrobial resistance among E.coli isolates there is growing concern worldwide as it has resulted in limited therapeutic options for treatment. Aims & objectives- To study distribution and antibiotic susceptibility pattern of E.coli in various clinical samples. Material & method- All samples received in Microbiology department at tertiary care hospital for culture and sensitivity were included in study. Culture positive sample with lactose fermenters were subjected to standard biochemical test for identification and antibiotic susceptibility testing was done along with distribution of E.coli in various samples was assessed. Results- Out of total 2585 samples received for culture & sensitivity, 1142 (44.17%) were culture positive of which 196 (17.16%) were E.coli isolates. Majority of E.coli isolates were from isolated from pus and wound swab 74 (37.75%) followed by urine sample 59 (30.10%) . Antibiotic sensitivity was maximum for imipenem 57%, amikacin 38% and piperacillin tazobactam 35%, nitrofurantoin 24%. Highest resistance was noted for ampicillin 96.5%, quinolones 91.33%, cephalosporins 91.33%