USE OF SYSTEMIC CORTICOIDS IN THE PATIENT WITH COVID-19 INFECTION:REPORT OF A CASE

Nataly Sofia Valdiviezo Allauca; Mayra Silvana Chavez Berrones; Stephany Soledad Martinez Hidalgo; Aida Rocio Arias Sarabia; Paul Alejandro Yanez Piedra; Andrea Estefania Montes Guerrero; Paola Alejandra Pillajo Vinueza

Volume : IX, Issue : VI, June - 2020

USE OF SYSTEMIC CORTICOIDS IN THE PATIENT WITH COVID-19 INFECTION:REPORT OF A CASE

Nataly Sofia Valdiviezo Allauca, Mayra Silvana Chavez Berrones, Stephany Soledad Martinez Hidalgo, Aida Rocio Arias Sarabia, Paul Alejandro Yanez Piedra, Andrea Estefania Montes Guerrero, Paola Alejandra Pillajo Vinueza

Abstract :

The new coronavirus outeak (2019-nCoV) is a great challenge for doctors. The clinical course of patients has not yet been fully characterized, few data are available to describe the pathogenesis of the disease, and there are still no proven pharmacological therapies.1 The main cynical practice guidelines, on the management of patients with WHO 2019-nCoV, make recommendations against the use of corticosteroids or mention avoiding their use; unless these are indicated for other medical conditions, which include exacerbation of COPD, asthma, or due to septic shock. However, a study published by the Cochrane Iberoamericano carried out a rapid review in order to respond to the use that corticosteroids were justified in the management of patients with 2019-nCoV.2 Regarding the published articles, one of the most cited was that of C. D. Russell, Millar and Baillie 2020; This article concludes that, as observed in other respiratory infections with other coronaviruses and influenza, there is no reason to expect that patients with SARS-CoV-2 infection will benefit from the use of corticosteroids, concluding that their use in early phase leads to benefits. 3 We present the case of an older adult patient with a history of allergic rhinitis, who reports having been exposed to family members with flu-like symptoms, presents respiratory symptoms based on cough, general malaise, anosmia and vomiting, goes to a specialized hospital where they carry out extension studies, highlighting slight neutrophilia and lymphopenia and nasopharyngeal swab: SARS-COV-2 Positive PCR in addition to ground glass pattern chest tomography, with favorable response to the use of prescribed systemic corticosteroids. Objective: To analyze the use of corticosteroids in hospital care practice for the treatment of COVID19. Method: This is a retrospective study. A case of a patient diagnosed with COVID pneumonia is reported, 19 highlighting the use of systemic corticosteroids in the early stages of the disease, obtaining favorable responses. Conclusion Coronaviruses (CoV) are a wide family of viruses that can cause a variety of conditions, from the common cold to more serious illnesses. The diagnosis is established by the clinic, laboratory and imaging studies, and for its definitive diagnosis is made by means of PCR in nasopharyngeal swab. Currently, there is no specific treatment, but an exhaustive investigation of the use of corticosteroids in the early phase of COVID 19 has been carried out, obtaining positive results, since it reduces the inflammatory response.