Volume : VI, Issue : IV, April - 2017

UTILITY OF PLASMA THROMBOPLASTIN CELL BLOCK TECHNIQUE IN CASES OF PLUERAL AND PERITONEAL EFFUSION SUSPECTED FOR MALIGNANCY

Dr. Savitri Shukla, Prerena

Abstract :

 Background- Cell block preparation act as a usefull adjunct on a smear cytology for diagnosis of pleural and peritoneal effusion by using plasma thromboplastin cell block technique. Diagnostic problem arises in day to day practice to differentiate reactive mesothelial cells and malignant cells  by conventional smears method, cell block technique  is easy required less time and showing  improved cytomorphological features  and  helps to differentiate reactive mesothelial cells and malignant cells and thereby increases diagnostic efficacy and additional benefits when used with routine cytology.  Material & method­- Total 168 cases are  studied out of which  majority of cases were reactive (n=154, 91.7%). Only 14 cases (8.3%) were malignant.  Among the reactive effusions, the commonest cause was tuberculosis (n=98, 58.3%). Result- There is statistically significant  increase in the frequency of malignant cells found on cell block technique as compared to conventional smear which is n=14 versus n=8. As 6 cases which were diagnosed as suspicious of malignancy on conventional smear were diagnosed as malignant in the sections of cell block. Conclusion-Increases in Cellularity,  better architecture display and morphological preservation in cell block technique aids in diagnosing the hidden cases of malignancy so it should be used as an adjunct to conventional smears to aid and improve the diagnosis in serous fluid cytology

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

Dr. Savitri Shukla, Prerena, UTILITY OF PLASMA THROMBOPLASTIN CELL BLOCK TECHNIQUE IN CASES OF PLUERAL AND PERITONEAL EFFUSION SUSPECTED FOR MALIGNANCY, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-6, Issue-4, April‾2017


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