Lumbar sympathetic block (LSB) and chemical sympathectomies are used for the pain treatment of Complex Regional Pain Syndrome (CRPS). 45-year-old patient was followed in our pain department with clinical signs and symptoms of CRPS after tibiofibular fracture. We did Lumbar sympathetic block with alcohol sympathectomy for several times for treatment reasons. After last procedure, patient experienced profound pain relief. But after 1week later, Groin pain with tingling sense in anterior thigh was developed as side effect. We assessed patient’s symptoms for Lumbar sympathetic block induced Genitofemoral neuralgia and lateral femoral cutaneous nerve injury. Therefore, we did psoas compartment block for diagnostic and therapeutic injection. The patient has had relief of pain for few months.