Where hypopituitarism is common but congenital hypopituitarism is rare. Severe prenatal deficiency of GH as occur in congenital hypopituitarism has little effect on fetal growth. Prenatal and congenital deficiency can reduce the size of male penis especially when gonadotropins are also deficient. Severe GH deficiency in early childhood also result in slower muscular development so that gross motor mile stone such as standing ,walking and jumping may be delayed. Bone age is helpful as it is usually delayed in patient with congenital Growth hormone deficiency.