<p>The present study was aimed to assess the effect of progressive muscle relaxation on quality of sleep among patients undergoing hemodialysis at Sree Gokulam Medical College Hospital, Trivandrum. The study used Quantitative approach and pre-experimental design. 42 Subjects were selected by convenient sampling technique from dialysis unit and used Pittsburgh sleep quality index (PSQI) to assess the quality of sleep and progressive muscle relaxation was given as intervention. First observation was done during first week followed by second observation during the second week in-order to get a baseline. Progressive muscle relaxation was taught with demonstration and advised to practice it for twice daily. Third observation was done after 4 weeks of intervention. The result showed that the mean PSQI score value in pretest as 8.85+/- 3.415 which were decreased to 4.69+/-1.70 after intervention. The difference in mean values were statistically significant (p<0.05). The paired t test value obtained is 8.778.The findings of the study revealed that progressive muscle relaxation can improve the quality of sleep among patients undergoing hemodialysis</p>