<p>Nursing has long been considered as one of the most stressful profession. A cross sectional survey was conducted with the objectives of assessing the job stress and its socio demographic correlates among fifty nurses working in the critical care units (Medical ICU, Post-operative ICU, CCU, Neuro ICU, Pediatric ICU, Neonatal ICU and Casualty) of selected Hospital, Trivandrum, which is a 600 bedded multi-specialty hospital. Samples recruited using random sampling method. Data was collected using a socio demographic Performa and Wolfgang health professions stress inventory scale. The main study was conducted after the approval of research committee .The findings revealed that majority of the subjects (52%) have moderate stress. 42% of the respondents have moderate stress and 6% of staff nurses have no stress. There was a significant association between area of working and level of stress (p=0.041) and also a significant association between experience in nursing profession and level of stress (p=0.015).</p>