<p> <b><u><span style="font-size:18.0pt;line-height:110%;
color:#0673A5;mso-themecolor:text2;mso-themeshade:191">AIMS</span></u></b><b><span style="font-size:18.0pt;line-height:110%;color:#0673A5;mso-themecolor:text2;
mso-themeshade:191"> </span></b><b><span style="font-size:22.0pt;line-height:
110%;color:#0673A5;mso-themecolor:text2;mso-themeshade:191">:</span></b></p> <p class="MsoListParagraphCxSpFirst" style="text-indent:-.25in;mso-list:l2 level1 lfo1"><!--[if !supportLists]--><span style="font-size:12.0pt;line-height:110%;font-family:Wingdings;mso-fareast-font-family:
Wingdings;mso-bidi-font-family:Wingdings">v<span style="font-variant-numeric: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: "Times New Roman";">  </span></span><!--[endif]--><span style="font-size:12.0pt;line-height:110%">Assess the level of HbA1c in relation to stroke.<o:p></o:p></span></p> <p class="MsoListParagraphCxSpLast" style="text-indent:-.25in;mso-list:l2 level1 lfo1"><!--[if !supportLists]--><span style="font-size:12.0pt;line-height:110%;font-family:Wingdings;mso-fareast-font-family:
Wingdings;mso-bidi-font-family:Wingdings">v<span style="font-variant-numeric: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: "Times New Roman";">  </span></span><!--[endif]--><span style="font-size:12.0pt;line-height:110%">To determine the relationship between HbA1c and diastolic dysfunction in stroke patients.<o:p></o:p></span></p> <p class="MsoNormal"><b><u><span style="font-size:18.0pt;line-height:110%;
color:#0673A5;mso-themecolor:text2;mso-themeshade:191">METHODS :<o:p></o:p></span></u></b></p> <p class="MsoListParagraphCxSpFirst"><span style="font-size:12.0pt;line-height:
110%">A cross-sectional hospital-based study was done which included 50 patients with stroke. Diastolic dysfunction was evaluated by Doppler echocardiography, in relation with age/sex   and HbA1c level in these patients. Data compiled & analysed in Microsoft Excel 2013 & Predictive analytics Software (SPSS) Vr. 11. Results shown in Frequencies and proportions. Sample   ‘t’ Significance tests applied. All stroke cases admitted in the department of General Medicine, ASRAMS, Eluru ,Andhra Pradesh, India between July 2015 to october 2016 were taken for the study.<o:p></o:p></span></p> <p class="MsoListParagraphCxSpMiddle"><span style="font-size:12.0pt;line-height:
110%"> </span></p> <p class="MsoListParagraphCxSpMiddle" style="margin-left:0in;mso-add-space:auto"><b><u><span style="font-size:18.0pt;line-height:110%;color:#0673A5;mso-themecolor:text2;
mso-themeshade:191">RESULTS :<o:p></o:p></span></u></b></p> <p class="MsoListParagraphCxSpMiddle"><span style="font-size:12.0pt;line-height:
110%"> </span></p> <p class="MsoListParagraphCxSpMiddle" style="margin-left:1.0in;mso-add-space:
auto;text-indent:-.25in;mso-list:l1 level1 lfo2"><!--[if !supportLists]--><span style="font-size:12.0pt;line-height:110%;font-family:Wingdings;mso-fareast-font-family:
Wingdings;mso-bidi-font-family:Wingdings">v<span style="font-variant-numeric: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: "Times New Roman";">  </span></span><!--[endif]--><span style="font-size:12.0pt;line-height:110%">The study showed that 74% of stroke patients had diastolic dysfunction.<o:p></o:p></span></p> <p class="MsoListParagraphCxSpLast" style="margin-left:1.0in;mso-add-space:auto;
text-indent:-.25in;mso-list:l1 level1 lfo2"><!--[if !supportLists]--><span style="font-size:12.0pt;line-height:110%;font-family:Wingdings;mso-fareast-font-family:
Wingdings;mso-bidi-font-family:Wingdings">v<span style="font-variant-numeric: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: "Times New Roman";">  </span></span><!--[endif]--><span style="font-size:12.0pt;line-height:110%">20 %   and 70 % were categorized as pre diabetic and diabetics respectively on the basis of HbA1c levels.<o:p></o:p></span></p> <p class="MsoNormal"><b><u><span style="font-size:18.0pt;line-height:110%;
color:#0673A5;mso-themecolor:text2;mso-themeshade:191"> </span></u></b></p> <p class="MsoNormal"><b><u><span style="font-size:18.0pt;line-height:110%;
color:#0673A5;mso-themecolor:text2;mso-themeshade:191"> </span></u></b></p> <p class="MsoNormal"><b><u><span style="font-size:18.0pt;line-height:110%;
color:#0673A5;mso-themecolor:text2;mso-themeshade:191">CONCLUSIONS :</span></u></b><span style="font-size:12.0pt;line-height:110%"><o:p></o:p></span></p> <p class="MsoListParagraphCxSpFirst" style="text-indent:-.25in;mso-list:l0 level1 lfo3"><!--[if !supportLists]--><span style="font-size:12.0pt;line-height:110%;font-family:Wingdings;mso-fareast-font-family:
Wingdings;mso-bidi-font-family:Wingdings">v<span style="font-variant-numeric: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: "Times New Roman";">  </span></span><!--[endif]--><span style="font-size:12.0pt;line-height:110%">This Study demonstrated a highly significant (positive) correlation between HbA1C level and frequency of diastolic dysfunction in stroke patients.<o:p></o:p></span></p> <p class="MsoListParagraphCxSpMiddle" style="text-indent:-.25in;mso-list:l0 level1 lfo3"><!--[if !supportLists]--><span style="font-size:12.0pt;line-height:110%;font-family:Wingdings;mso-fareast-font-family:
Wingdings;mso-bidi-font-family:Wingdings">v<span style="font-variant-numeric: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: "Times New Roman";">  </span></span><!--[endif]--><span style="font-size:12.0pt;line-height:110%">Higher HbA1c level is a reliable predictor of diastolic dysfunction in stroke patients.<o:p></o:p></span></p> <p class="MsoListParagraphCxSpMiddle" style="text-indent:-.25in;mso-list:l0 level1 lfo3"><!--[if !supportLists]--><span style="font-size:12.0pt;line-height:110%;font-family:Wingdings;mso-fareast-font-family:
Wingdings;mso-bidi-font-family:Wingdings">v<span style="font-variant-numeric: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: "Times New Roman";">  </span></span><!--[endif]--><span style="font-size:12.0pt;line-height:110%">Hence we recommend HbA1c level as an independent predictor of stroke.<o:p></o:p></span></p> <p class="MsoListParagraphCxSpMiddle" style="text-indent:-.25in;mso-list:l0 level1 lfo3"><!--[if !supportLists]--><span style="font-size:12.0pt;line-height:110%;font-family:Wingdings;mso-fareast-font-family:
Wingdings;mso-bidi-font-family:Wingdings">v<span style="font-variant-numeric: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: "Times New Roman";">  </span></span><!--[endif]--><span style="font-size:12.0pt;line-height:110%">Doppler Echocardiography is a simple noninvasive valuable tool in diagnosing diastolic dysfunction.<o:p></o:p></span></p> <p class="MsoListParagraphCxSpMiddle" style="text-indent:-.25in;mso-list:l0 level1 lfo3"><!--[if !supportLists]--><span style="font-size:12.0pt;line-height:110%;font-family:Wingdings;mso-fareast-font-family:
Wingdings;mso-bidi-font-family:Wingdings">v<span style="font-variant-numeric: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: "Times New Roman";">  </span></span><!--[endif]--><span style="font-size:12.0pt;line-height:110%">Diabetic patients have higher tendency to develop Diastolic dysfunction which is usually undiagnosed.<o:p></o:p></span></p> <p class="MsoListParagraphCxSpLast" style="text-indent:-.25in;mso-list:l0 level1 lfo3"><!--[if !supportLists]--><span style="font-size:14.0pt;line-height:110%;font-family:Wingdings;mso-fareast-font-family:
Wingdings;mso-bidi-font-family:Wingdings">v<span style="font-variant-numeric: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: "Times New Roman";"> </span></span><!--[endif]--><span style="font-size:12.0pt;line-height:110%">Thus, early Echocardiography is advised in all diabetics to assess the cardiac function</span><span style="font-size:14.0pt;line-height:110%"><o:p></o:p></span></p>