<?xml version="1.0" encoding="UTF-8"?><article>
	<front>
		<journal-meta>
			<journal-id journal-id-type="publisher">GJRA</journal-id>
			<journal-title>GJRA - Global Journal For Research Analysis</journal-title>
			<issn pub-type="ppub">2250 - 1991</issn>
			<publisher>
				<publisher-name>Indian Society for Health and Advanced Research</publisher-name>
			</publisher>
		</journal-meta>
		<article-meta>
			<article-id pub-id-type="other">gjra-7-11-9706</article-id>
			<article-categories>
				<subj-group>
					<subject>Original Research Paper</subject>
				</subj-group>
			</article-categories>
			<title-group>
				<article-title>STUDY OF CLINICOHEMATOLOGICAL PROFILE AND NEUROLOGICAL MANIFESTATIONS OF VITAMIN B 12 DEFICIENCY IN CHILDREN</article-title>
			</title-group>
			<contrib-group><contrib contrib-type="author">
						<name>
							<surname></surname>
							<given-names></given-names>
							<prefix>Dr.</prefix>
						</name>
						<xref ref-type="aff" rid="aff000">
							<sup></sup>
						</xref>
						</contrib></contrib-group><pub-date pub-type="ppub">
				<month>November</month>
				<year>2018</year>
			</pub-date>
			<volume>7</volume>
			<issue>11</issue>
			<fpage>01</fpage>
			<lpage>02</lpage>
			<abstract>
				<title>ABSTRACT</title>
				<p>&amp;lt;p&amp;gt;&amp;amp;nbsp;&amp;lt;/p&amp;gt;
&amp;lt;p class=&quot;MsoNormal&quot; style=&quot;margin-bottom:0in;margin-bottom:.0001pt;text-align:&amp;amp;#10;justify;line-height:200%&quot;&amp;gt;&amp;lt;span style=&quot;font-family:&amp;amp;quot;Times New Roman&amp;amp;quot;,&amp;amp;quot;serif&amp;amp;quot;;&amp;amp;#10;color:black&quot;&amp;gt;Vitamin B12 deficiency is an important and under recognised cause of anemia and neurological morbidity in&amp;lt;/span&amp;gt;&amp;lt;span style=&quot;font-family:&amp;amp;quot;Times New Roman&amp;amp;quot;,&amp;amp;quot;serif&amp;amp;quot;&quot;&amp;gt; children&amp;lt;span style=&quot;color:black&quot;&amp;gt;.&amp;lt;/span&amp;gt; As per previous studies from India iron deficiency was most common cause for anemia. But from the past two to three decades prevalence of cobalamin deficiency is increasing. This study aims to &amp;lt;span style=&quot;color:black&quot;&amp;gt;study the various clinical, neurological manifestations and hematologic profile of Vitamin B12 deficiency anemia in children aged 6 months to 12 years.&amp;lt;/span&amp;gt; A total of 58 children with Vitamin B12 deficiency were studied of which the most common age group affected were 1 to 4 years. Pallor, Anorexia, generalised weakness (100%), &amp;lt;span style=&quot;color:black&quot;&amp;gt;hyper pigmented knuckles (94%) and Hyper pigmented distal phalanges (90%), &amp;lt;/span&amp;gt;&amp;lt;/span&amp;gt;&amp;lt;span class=&quot;A7&quot;&amp;gt;&amp;lt;span style=&quot;font-size:9.0pt;line-height:200%;font-family:&amp;amp;quot;Times New Roman&amp;amp;quot;,&amp;amp;quot;serif&amp;amp;quot;&quot;&amp;gt;Glossitis (68%) were the most common presentations. &amp;lt;/span&amp;gt;&amp;lt;/span&amp;gt;&amp;lt;span style=&quot;font-family:&amp;amp;#10;&amp;amp;quot;Times New Roman&amp;amp;quot;,&amp;amp;quot;serif&amp;amp;quot;;color:black&quot;&amp;gt;The neurological features were seen in all the cases in 6 &amp;amp;ndash; 12 month age group. Leucopenia was seen in 74% and Thrombocytopenia in 49% cases. &amp;lt;/span&amp;gt;&amp;lt;span class=&quot;A11&quot;&amp;gt;&amp;lt;span style=&quot;font-size:&amp;amp;#10;9.0pt;line-height:200%;font-family:&amp;amp;quot;Times New Roman&amp;amp;quot;,&amp;amp;quot;serif&amp;amp;quot;&quot;&amp;gt;Early identification and treatment can prevent irreversible brain injury and its profound impact on neurological outcome of child.&amp;lt;/span&amp;gt;&amp;lt;/span&amp;gt;&amp;lt;b style=&quot;mso-bidi-font-weight:&amp;amp;#10;normal&quot;&amp;gt;&amp;lt;span style=&quot;font-family:&amp;amp;quot;Times New Roman&amp;amp;quot;,&amp;amp;quot;serif&amp;amp;quot;&quot;&amp;gt;&amp;lt;o:p&amp;gt;&amp;lt;/o:p&amp;gt;&amp;lt;/span&amp;gt;&amp;lt;/b&amp;gt;&amp;lt;/p&amp;gt;</p>
			</abstract>			
			<counts>
				<ref-count count="7"/>
				<page-count count="2"/>
			</counts>
		</article-meta>
	</front>
</article>