ABSTRACT

GJRA

GJRA - Global Journal For Research Analysis

2250 - 1991

Indian Society for Health and Advanced Research

gjra-7-11-9744

Original Research Paper

A CLINICAL COMPARATIVE STUDY OF TWO INTUBATING DOSES OF CIS-ATRACURIUM DURING GENERAL ANAESTHESIA FOR RENAL TRANSPLANT SURGERIES.

Akruti

Modi

Dr.

November 2018

7 11 01 02 ABSTRACT

&nbsp;Introduction: Cisatracurium unlike atracurium is devoid of histamine-induced cardiovascular effects and this alone would be the greatest advantage in replacing atracurium for the facilitation of tracheal intubation. On the other hand, 2xED95 dose of cisatracurium (100micro/kg) do not yield satisfactory intubating conditions such as those seen with equipotent doses atracurium and therefore there commended intubating dose of cisatracurium is 3xED95 . To understand better, we evaluated intubating condition with diferent doses of cisatracurium in renal transplant surgery. Aims &amp; objectives: To evaluate and compare the intubating condition, duration of action, hemodynamic effects for different doses of cisatracurium.<o:p></o:p> Material &amp; methods: After informed patient&rsquo;s consent 60 patients in age group of 20-50 years were selected and included in the study. Patients were divided in two groups of 30 each, GROUP-A received intravenously 2&times;ED95 (0.1mg/kg) dose of cisatracurium and GROUP-B received intravenously 3&times;ED95 (0.15mg/kg) during induction.<o:p></o:p> <span lang="EN-IN" style="font-size:14.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;;&#10;mso-fareast-font-family:&quot;Times New Roman&quot;;mso-fareast-theme-font:minor-fareast;&#10;mso-ansi-language:EN-IN;mso-fareast-language:EN-GB;mso-bidi-language:AR-SA">&nbsp;Results :Better intubating condition,hemodynamic stability and longer duration of action was found with 0.15mg/kgdose of Cisatracurium than 0.1mg/kg Cisatracurium in a induction&nbsp;