A STUDY OF THE ANGIOGRAPHIC PROFILE AND RISK FACTORS IN PATIENTS OF ISCHEMIC STROKE

COL (DR) SANJAY I TOTLANI; BRIG (DR) ARUN TYAGI

Volume : VII, Issue : I, January - 2017

A STUDY OF THE ANGIOGRAPHIC PROFILE AND RISK FACTORS IN PATIENTS OF ISCHEMIC STROKE

Col Dr Sanjay I Totlani, Brig Dr Arun Tyagi

Abstract :

Introduction: Stroke is the third commonest cause of death in India and there is a higher incidence of stroke in young in India than in the developed countries. Ischemic stroke accounts for 70–85% of all strokes. The present study was conducted in a tertiary level large neurological centre between 2007–2009 to study the risk factors associated with ischemic stroke and its correlation with angiographic profile. Material & Methods: In this study group of 161 patients, patients were between 15–70 years of age and all cases included were those who presented with first ever ischemic stroke. Patients were assessed for conventional risk factors for stroke and also procoagulant factors. All patients underwent a DSA of neck and intracranial vessels. The DSA profile was then correlated with their risk factors. Results: Angiographic abnormalities were found in 36% of patients, most of the abnormalities were in extracranial vasculature. Intracranial vascular lesions were seen in 14% of patients which is much higher than western literature where intracranial disease was in 4–6% of cases. Conclusion: There was no significant statistical difference between the two groups; the patients with angiographic abnormalities and had risk factors vs those who had angiographic abnormalities but had no risk factor. Thus, risk factors do not predict the likelihood of angiographic abnormality. Other significant conclusion was that stroke in young (17–45yrs) had more procoagulant abnormalities and those in the middle aged and elderly had more of conventional risk factors.