Advantage Of Fallopian Tube Sperm  Perfusion Over Intra–uterine Insemination When  Used In Combination With Ovarian Stimulation  For The Treatment Of Unexplained Infertility.

Dr G S Shekhawat; Dr Pushpalata Naphade

Volume : I, Issue : V, February - 2012

Advantage Of Fallopian Tube Sperm Perfusion Over Intra–uterine Insemination When Used In Combination With Ovarian Stimulation For The Treatment Of Unexplained Infertility.

Dr G S Shekhawat, Dr Pushpalata Naphade

Abstract :

200 consecutive patients with infertility in 404 stimulated cycles were included in the study. Those randomized to standard IUI included 100 patients in 184 cycles [158 clomiphene citrate/human menopausal gonadotrophin cycles and 26 Letrozole/FSH cycles exclusively for polycystic ovarian disease patients] (group A). Patients subjected to FSP included 100 patients in 220 cycles (193 clomiphene citrate/human menopausal gonadotrophin cycles and 27 Letrozole / FSH cycles exclusively for polycystic ovarian] (group B). Swim up semen preparation technique was used in all cases. Insemination was performed in both groups 34 hours after hCG administration. Standard IUI was performed using 0.5 ml of inseminate. In FSP 4ml inseminate was used. In group A (184 IUI cycles in 100 patients), 22 clinical pregnancies occurred (11.95% per cycle). In group B, (220 cycles of FSP in 100 patients), 48 clinical pregnancies occurred (21.81%per cycle). For non–tubal sub fertility, the results indicate clear benefit for FSP (Fallopian tube sperm perfusion) over IUI (Intrauterine insemination).