Analysis The Nephro Protective Activity of The Oleanolic Acid Isolated from The Medicinal Plant–Cassia Auriculata (Linn.)

P.K. Senthilkumar; K. Gajendiran

Volume : III, Issue : VII, July - 2014

Analysis The Nephro Protective Activity of The Oleanolic Acid Isolated from The Medicinal Plant–Cassia Auriculata (Linn.)

P. K. Senthilkumar, K. Gajendiran

Abstract :

The nephro protective activity was studied using male albino rats of Wistar strain by treatment with oleanolic acid. The treatment with oleanolic acid at 50 mg/kg was found to reduce the level of urea for (23.73 mg/dL) as well as creatinine (0.64 mg/dL). The results showed that the administration of oleanolic acid significantly decreased the levels of MDA, urea and creatinine in Gentamycin–induced rats.