Carotid Intima Media Thickness in metabolic syndrome  An Indian Perpective

Nisha Jose; Samuel Hansdak; Jacob Jose; Thenmozhi mani

Volume : VI, Issue : III, March - 2016

Carotid Intima Media Thickness in metabolic syndrome An Indian Perpective

Nisha Jose, Samuel Hansdak, Jacob Jose, Thenmozhi Mani

Abstract :

BACKGROUND: Carotid Intima Media Thickness (CIMT) is a surrogate marker for atherosclerosis. It correlates well with incident heart disease or stroke. In this study we used CIMT as a marker of atherosclerosis to identify individuals at high risk of cardiovascular disease in a group of subjects with Metabolic syndrome in a tertiary care hospital in South India METHODS: 116 subjects in the age group of 45to 60 years were enrolled to look at the CIMT. A cut off value of 0.8 mm or more was used to identify the high risk group, in an observational study design. Measurement was taken at 6 sites of the carotid. The results were analysed using chi square tests and multivariate logistic regression analysis to control for traditional risk factors. RESULTS: We found that the prevalence of high CIMT was 10.34%. CIMT was found to be significantly associated with Metabolic syndrome (p value of ‹0.001). Other traditional risk factors like diabetes, hypertension, and dyslipidemia were not significantly associated with elevated CIMT. The best site for measurement of CIMT was the internal carotid. CONCLUSIONS: Metabolic syndrome is significantly associated with CIMT. The risk attributable to Metabolic syndrome is over and above the risk conferred by individual risk factors or combinations of them. The site which gives the best pick up rate of high CIMT is the internal carotid.