Volume : IV, Issue : II, February - 2014

Clinico–Mycologicalprofile of Vaginal Candidiasis in A Tertiary Care Hospital

Dr. Velvizhi G, Dr. Sucilathangam G, Dranna. T

Abstract :

Candida species are opportunistic yeasts affecting the genitourinary tracts. A study was carried out to determine the frequency of vaginal candidiasis and the susceptibility profile of the Candida species to antifungal agents. The study was carried out prospectively in Tirunelveli Medical College Hospital, Tamil Nadu during August and September, 2013. 50 vaginal swabs were collected from sexually active women in the age group of 18-45 and cultured, out of which 12(24.00%) were positive for Candida species. They were tested for antifungal susceptibility by disk diffusion method. C. parapsilosis (58.33%) was the predominant species isolated followed by C. albicans (25.00%) and C. glaata (16.67%). The highest frequency of vaginal candidiasis was seen in the age group of (26-35). Usage of antibiotics was the most frequently implicated risk factor (41.67%). Susceptibility testing revealed that 66.67% of C.albicans, 50% of C. glaata and 57.14% of C. parapsilosis were sensitive to Itraconazole, 66.67% of C. albicans were sensitive to Fluconazole. 57.14% of C. parapsilosis were sensitive to Clotrimazole and 71.43% were sensitive to Miconazole.In conclusion, an increase in non-albicans Candida infections and the emergence of Azole resistant C. albicans and non-albicans species which emphasizes the need for species identification and antifungal susceptibility as a part of laboratory diagnosis of vaginal candidiasis.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Velvizhi G, Dr.Sucilathangam G, DrAnna.T Clinico-Mycologicalprofile of Vaginal Candidiasis in A Tertiary Care Hospital Indian Journal of Applied Research, Vol.IV, Issue. II

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