Volume : VIII, Issue : IV, April - 2018

Cytological diagnosis of Pulmonary alveolar proteinosis from bronchoalveolar lavage specimen - A case report of silicoproteinotuberculosis and review of literature

Dr. Ajithakumari K, Dr. Radhika Pillai

Abstract :

 We present a case  report  of  unusual  association  of  silicosis, pulmonary  alveolar  proteinosis  and  tuberculosis  occurring in a  30  year  old stone  quarry  worker  exposed  to  sand  dust  since 15  years. Pulmonary alveolar  proteinosis  (PAP) is an  uncommon  disease   in  which there  is  progressive  and inappropriate  occupation  of  the  lung  alveoli by  an  excessive amount  of  unprocessed  surfactant. Untill  recently the  gold  standard   for  diagnosis  of PAP was  considered  to be   open  lung  biopsy followed  by  histopathological  and ultrastructural  examination.With  the introduction  of  improved    onchoscopic  techniques,  onchoalveolar lavage (BAL)  is  now  employed  as  a  useful  diagnostic  and  therapeutic  modality  in  the  management  of  PAP.  The  cytological features  of  BAL fluid  in  PAP are  unique  and  with supporting  clinical  and  radiological  evidences  a  confident  diagnosis  of  PAP  can  be  given  so that the  patient  can  be  spared  of  a  more  invasive diagnostic  procedure. The  authors  present  a  case  report  where  a cytological  diagnosis  of  PAP was  made  possible  by  routine  Papanicolaou  stained  smears  and  PAS–D  stains. The  utility  of  BAL cytology  in  the  diagnosis  of  PAP  is  discussed.The conclusion  is  that study  of  the  onchoscopic  lavage  fluid  is  a useful  diagnostic  modality  in  PAP. 

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Ajithakumari K, Dr.Radhika Pillai, Cytological diagnosis of Pulmonary alveolar proteinosis from bronchoalveolar lavage specimen‾A case report of silicoproteinotuberculosis and review of literature, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-4 | April-2018

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