Early osteoporosis caused by usage of Nicotine (smoking and chewing) In postmenopausal women in rural Andhra Pradesh

B. Madhava Rao; Prof MK Sagar.; Gowtham. B.; SKSS Satish Reddy; A. Sucharita; NM Sampath Anil Kumar

Volume : X, Issue : V, May - 2020

Early osteoporosis caused by usage of Nicotine (smoking and chewing) In postmenopausal women in rural Andhra Pradesh

B. Madhava Rao, Prof Mk Sagar. , Gowtham. B. , Skss Satish Reddy, A. Sucharita, Nm Sampath Anil Kumar

Abstract :

Nicotine use in any form ( chutta is tobacco leaf smoking, chewable forms like khaini, gutkha), studied in 120 postmenopausal women in 2 districts of Rural Andhra Pradesh state viz., Srikakulam and Vizianagaram revealed in causation of early osteoporosis compared to non–users of nicotine, even second hand smoking also affected womens health. Nicotine use in any form (smoking,chewable forms) showed reduced levels of estrogens in postmenopausal women. Inverse relationship exists between nicotine users and in the serum estradiol levels. Among nicotine users in any form there was increased hepatic clearance of estrogens in postmenopausal women contributing to enhanced risk of osteoporosis.