Volume : IV, Issue : I, January - 2014

Efficacy of Clonidine as an Adjuvant to Lignocaine Infiltration for Prolonged Analgesia After Episiotomy

Dr. Noopur D. Singh, Dr. Shalini K. Thombre, Dr. Smita G. Saundattikar

Abstract :

Background: Clonidine, an alpha 2 adrenergic receptor agonist, has been used as an adjuvant with local anaesthetic agents to prolong the duration of peripheral nerve blocks.

Objectives: The purpose of our study was to compare the efficacy of clonidine 1 mcg/kg with 2% lignocaine and 2% lignocaine alone in prolonging the duration of analgesia after episiotomy with respect to various activities like sitting, walking and squatting.

Methods: A total of 60 female patients, aged 20-40 years, of ASA grade I and II, scheduled for full term vaginal delivery were assigned into two groups of 30 each, lignocaine group (L) and lignocaine- clonidine group (C).Group L received 7 ml of 2% lignocaine while Group C received 7 ml of 2% lignocaine to which 1 mcg/kg of clonidine was added. Haemodynamic parameters and pain scoring using the VAS were monitored. At the end of the research project, the data was compiled systematically and analyzed using appropriate statistical tests by a statistician. Value of p< 0.05 was considered significant and p< 0.001 as highly significant.

Results: Duration of analgesia after episiotomy was significantly prolonged in Group C as compared with Group L with respect to various activities.

Conclusion: Clonidine when added to 2% lignocaine for infiltration before episiotomy clearly improves the quality and prolongs the duration of sensory analgesia obtained.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Noopur D. Singh, Dr. Shalini K. Thombre, Dr. Smita G. Saundattikar Efficacy of Clonidine as an Adjuvant to Lignocaine Infiltration for Prolonged Analgesia After Episiotomy Indian Journal of Applied Research, Vol.IV, Issue. I


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